Background

The COVID-19 pandemic underscored the urgent need for advanced models of infectious respiratory diseases. Current cell culture systems fail to mimic the complexity of the human lung, while animal models lack essential properties of the human pulmonary blood-air barrier, often requiring costly humanized transgenic systems.

To advance understanding, there is a need for experimental platforms that reproduce the pulmonary microphysiology, particularly the alveolar epithelial cells targeted by SARS-CoV-2. Such models can reveal mechanisms of viral entry and progression, while supporting the evaluation of novel therapeutic interventions.

The project

MicroLung pursues the following objectives:

• Develop pulmonary blood-air barrier models using microfluidic and tissue-engineered systems.
• Design nanoparticles functionalized with ACE2-specific peptides to mimic viral binding and compete with SARS-CoV-2 for cell entry.
• Engineer nanoparticles carrying antiviral agents for drug transport studies across the lung barrier.
• Validate models with SARS-CoV-2 isolates in biosafety level 3 laboratories to compare nanoparticle results with actual viral behavior.
• Foster transnational collaboration between partners for nanoparticle design, microfluidic systems, and virus validation studies.

The science

The consortium integrates complementary expertise:

• Microfluidic and tissue engineering platforms to recreate the pulmonary barrier (ACU, Turkey).
• Nanoparticle-based therapeutic delivery systems and functional testing (Fraunhofer IKTS, Germany).
• In-vitro infection studies with SARS-CoV-2 isolates in biosafety level 3 facilities (UGM, Indonesia).

Outcomes include novel lung models for COVID-19 research, nanoparticle-based therapeutic concepts, and platforms applicable to other respiratory viruses beyond SARS-CoV-2.

The team

The MicroLung partners are:

Prof. Dr. Vasif Nejat Hasirci (Coordinator), Acibadem Mehmet Ali Aydinlar University (ACU), Turkey

Dr. Joerg Opitz, Fraunhofer Institute for Ceramic Technologies and Systems (IKTS), Germany

Assoc. Prof. Ika Dewi Ana, Universitas Gadjah Mada (UGM), Indonesia

Contact:

Prof. Dr. Vasif Nejat Hasirci           Email: vasif.hasirci@acibadem.edu.tr 

Background

The COVID-19 pandemic and earlier coronavirus outbreaks (SARS, MERS) demonstrate the ongoing threat of zoonotic spillovers. Vaccines inducing both antibody and T-cell responses against conserved viral regions are essential. However, T-cell epitopes vary across populations due to differences in HLA allele prevalence.

Most studies so far have focused on Caucasian populations, neglecting alleles like HLA-A*24:07, common in Southeast Asia. This project brings together partners from Indonesia, Thailand, and Germany to identify SARS-CoV-2-specific epitopes relevant to these populations, filling a major research gap.

The project

TimCovSEAEu pursues the following objectives:

• Identification of T-cell epitopes: Use immunoinformatics algorithms (SYFPEITHI, NetMHCpan) to predict SARS-CoV-2 CD4+ and CD8+ epitopes for the most frequent HLA class I (15 alleles) and HLA-DR (6 alleles) in Southeast Asia.
• Experimental validation: Conduct high-throughput ELISpot assays using PBMCs from COVID-19 convalescent donors to confirm T-cell responses.
• Immunological characterization: Compare T-cell responses in COVID-19 convalescents versus uninfected individuals to assess immunity and memory.
• Application for vaccines and immunotherapies: Provide candidate epitopes for multi-peptide vaccines and adoptive T-cell therapies.

The science

The consortium integrates computational prediction with experimental validation:

• Immunoinformatics analysis of the SARS-CoV-2 proteome.
• High-throughput epitope screening using ELISpot assays.
• Comparative immunology across Indonesian, Thai, and European cohorts.
• Clinical translation through collaboration with hospitals and immunotherapy centers.

Expected outcomes include novel epitope panels for monitoring T-cell memory, deeper insights into cross-population immunity, and candidate structures for next-generation vaccines and therapies.

The team

The TimCovSEAEu partners are:

Ph.D. Marsia Gustiananda (Coordinator), Indonesia International Institute for Life Sciences (i3L), Indonesia

PD Dr. med. Juliane Sarah Walz, Robert Bosch Center for Tumor Diseases, Robert Bosch Hospital Stuttgart (RBCT), Germany

Assist. Prof. Jaturong Sewatanon, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand

Contact:

Ph.D. Marsia Gustiananda               Email: marsia.gustiananda@i3l.ac.id 

Background

Rechargeable Li–sulfur (Li-S) batteries promise much higher energy density (up to 2570 Wh/kg) compared to Li-ion batteries. However, commercialization is hindered by two main challenges: the insulating nature of sulfur and the shuttle effect caused by dissolved lithium polysulfides, which reduce active material and lead to rapid capacity fading.

Nanostructured materials offer a rational solution. Two-dimensional MXenes (transition metal carbides, nitrides, carbonitrides) and transition metal oxides (TMOs) can be engineered into heterostructures to immobilize LiPSs and catalyze their conversion, enabling both high sulfur loading and reduced shuttle effects. 

The project

ECO-MX pursues the following objectives:

• Construction of MXene-TMO heterostructures with maximally exposed chemisorption sites for LiPSs, enhancing conversion kinetics and sulfur utilization.
• Development of multifunctional electrodes and separators to suppress the shuttle effect and improve electrochemical performance.
• Characterization and mechanism studies using advanced techniques (XRD, XANES, high-resolution microscopy) to evaluate LiPSs kinetics.
• Fabrication and testing of demonstrator Li-S cells (coin and pouch cells) to validate performance improvements in real battery conditions.

The science

The project integrates expertise in materials science, catalysis, and energy storage:

• MXene synthesis and heterostructure design (Empa, Switzerland).
• In-situ characterization of LiPS conversion processes (ENTEC, Thailand).
• Membrane and separator engineering using nanofiber-based ultrathin porous films with MXene-TMO integration (Sabanci University, Turkey).

Final demonstrators will combine all components into coin and pouch cells, tested against reference batteries. The research builds directly on global initiatives in energy storage, including links to Europe’s Battery2030+ program.

The team

The ECO-MX partners are:

Dr. Jakob Heier (Coordinator), Empa – Swiss Federal Laboratories for Materials Science and Technology, Switzerland

Dr. Pimpa Limthongkul, National Energy Technology Center (ENTEC) – NSTDA, Thailand

Prof. Selmiye Alkan Gürsel, Sabanci University Nanotechnology Research and Application Center (SUNUM), Turkey

Contact: 

Dr. Jakob Heier              Email: jakob.heier@empa.ch 

Background

Nanotechnology, the science of construction at nanoscale, has multiple applications in medicine, industry, and ICT. In recent years, peptides have emerged as promising therapeutic molecules for conditions like hypertension, epilepsy, chronic pain, and cancer. However, peptides are prone to enzymatic digestion and can trigger unwanted immune responses.

Nanoparticles can act as carriers to protect peptides, control their release, and improve efficacy. Designing bioactive peptide analogs and peptide–nanoparticle systems offer opportunities to treat diseases more safely and effectively, while also enabling biomedical imaging through fluorescent labeling. This project builds on advances in synthetic chemistry, nanomaterials, and neuropharmacology.

The project

PEP-NANO-DRUG pursues several specific objectives (SOs):

• Synthesis and characterization of new Spinorphin analogs with anticonvulsant and antinociceptive actions.
• Development of hybrid peptide derivatives incorporating electron-donating and electron-withdrawing groups with photoactive properties for biomedical applications.
• Preparation of nano-peptide systems using metal-based nanoparticles for delivery of therapeutic peptide molecules.
• Characterization of nano-peptide properties and evaluation of their biological applications.
• Medico-biological evaluation of synthesized nano-peptides to assess therapeutic efficacy and safety.

The science

The project integrates synthetic peptide chemistry, nanotechnology, and neurobiology:

• Engineering novel peptide analogs with enhanced stability and therapeutic action.
• Functionalizing peptides with fluorophores for dual therapeutic and imaging purposes.
• Employing nanoparticles as drug carriers to protect peptides from degradation and allow controlled release.
• Evaluating anticonvulsant and antinociceptive activities in biological systems.

The team

The PEP-NANO-DRUG partners are:

Assoc. Prof. PhD Stela Georgieva-Kiskinova (Coordinator), University of Chemical Technology and Metallurgy – Sofia (UCTM), Bulgaria

Dr. Hoa Le, Institute for Nanotechnology (INT), Vietnam National University – Ho Chi Minh City, Vietnam

Assoc. Prof. Subaer Subaer, Universitas Negeri Makassar, Indonesia

Contact: Assoc. Prof. PhD Stela Georgieva-Kiskinova            Email: st.georgieva@uctm.edu 

Background

Cancer therapies such as chemotherapy and radiotherapy save lives but frequently destroy ovarian function in women of childbearing age. Fertility preservation methods like ovarian tissue cryobanking present risks of reintroducing malignant cells in some cancer types. Therefore, innovative strategies are needed to restore fertility safely.

The BioOva project addresses this by creating a bioinspired engineered ovary capable of replicating the supportive environment of a natural ovary. This approach integrates tissue engineering, nanotechnology, and reproductive biology to provide a safer and more effective fertility restoration solution for cancer patients.

The project

BioOva pursues three specific objectives (SOs):

• Development of BioOva 3D matrix (WP1-3): A temporary hydrogel (3Dgel) will be engineered with defined stiffness and stability, functionalized with ECM components, and validated in vitro and in vivo.
• Development of BioOva nanoparticles (WP4-6): Nanoparticles will be designed to encapsulate and release bioactive signaling factors, enabling controlled and sustained delivery to support folliculogenesis.
• Assessment of BioOva (WP7-8): The system’s ability to support complete folliculogenesis will be evaluated, with the aim of producing healthy oocytes for in vitro maturation.

The science

BioOva integrates nanotechnology, biomaterials, and reproductive biology:

• Development of synthetic hydrogels mimicking the ovarian extracellular matrix.
• Use of nanoparticle delivery systems for controlled release of biofactors, ensuring biocompatibility and signaling efficacy.
• Application of advanced molecular techniques to assess follicle survival, growth, and maturation in engineered environments.

The project builds on expertise in biomaterials, proteomics, reproductive biology, and fertility preservation from leading European and Southeast Asian partners.

The team

The BioOva partners are:

Prof. Dr. Christiani Andrade Amorim (Coordinator), Université Catholique de Louvain (UCLouvain), Belgium

Dr. Martin Ehrbar, University of Zurich (UZH), Switzerland

Assist. Prof. Dr. Paweena Thuwanut, Chulalongkorn University (CU), Thailand

Contact:

Prof. Dr. Christiani Andrade Amorim                  Email: christiani.amorim@uclouvain.be 

Background

Contemporary hospitality industry faces difficulties maintaining reputation, which is vital for South East Asia where quality and responsible customers are needed in times of tourism boom and looming danger of pollution. In fact, the reputation concept has been widely used since old times, in many areas. For example, selecting doctors or dentists based on their reputation constructed by other friends, getting married with a person based on family and friends’ suggestions or selection of university to attend based on reputation constructed by past students etc. In an organized world, institutions and certifications replaced classical “word of mouth”-based reputation, whereas doctors, universities, companies are rated or accredited by individual institutions who are expert and recognized by the government and trusted as accrediting institutions.

Yet, the ever increasing power of internet, social media and user generated content, revived centuries old “word of mouth”-based reputation. This, on the other hand brings its own special problems to tackle. Vast amount of data generated turns into a big data problem to be solved and processed, whereas credibility of each user generated data becomes questionable. Users, generate star ratings, comments, stories, blogs, tweets and many different content about the experience they had from the service or goods. These are usually incomplete, varying in quality and credibility and vague in general. This in turn increases the pressure onto the emerging forms of cooperative sustainable tourism that does not have the solid market power of multinational chains.

The project

The proposal aims to create a distributed bidirectional cross-reputation rating and review service for hotel and tourism industry that can be used through multiple countries, in transboundary transactions, for sustainable, cooperative business. ROBTI is thus in pursuit of several specific objectives (SOs):

• Prototyping software algorithms that validate research on cross-reputation rating and review service for the hospitality sector, blockchain and cooperatives.
• Combining together holistically concepts and approaches from disciplines in computer science, urbanism, environmental studies, tourism science, and management.
• Creating an integrated decentralised system for rating and review ready for demonstration and validation in tourism.
• Contributing to the transformation of the hospitality industry into sustainable, inclusive, cooperative model of transboundary business that is rated by trustworthy distributed rating.

The science

 ROBTI is aligned with concepts such as sustainability and climate-resilience applied to the tourism industry. It aims to combine other aspects of the project with making the hotel business ‘greener’: reducing the carbon imprint of the hospitality sector onto the environment, hotels shall also build resilience in the local community of the tourism destination to disasters. The research by STMIK and further studies to be done within the project will enable disaster resilient hotels to become major catalysts in managing disasters in the destination area.

ROBTI combines studies and applied research about ICT tools for payments of transboundary transactions and cooperative tourism operations, blockchain technology for distributed review and ranking in the tourism industry and machine learning for trust rate calculation, natural language processing and sentiment analysis. To that extent, the industrial partners (Protel and Setur) and Gebze Techical University have previous research that the project will build upon.

The team

The ROBTI partners are:

Alphan Kimyonok (Coordinator), Meltem Turhan Yöndem, Cenk Yusuf Ustabaş, Müslim Erdal Şekerci, Anıl Özdemir, Mustafa Çelen, İsa Öztürk, Setur,Turkey

Hüseyin Atun, Hakan Özkırım, Tolga Gezginiş, Hasan Soysal, Batuhan, Çoşkun, Protel, Turkey

Assoc. Prof. Mehmet Göktürk, Gebze Techncical University, Turkey

Tri A. Sundara,STMIK Indonesia Padang, Indonesia

Contact:

Cenk Yusuf Ustabaş         

Background

The current antibiotic crisis represents a global problem of fundamental importance, comparable with other global challenges as e.g. climate change or sustainable energetics, but far less discussed in the society. Without active approach right now the, the infectious diseases will soon become the most frequent cause of death worldwide.

The TIC-TAC project consists of two objectives aiming to avert the threat of an antibiotic crisis: 1) Knowledge-based hunt for novel bioactive metabolites derived from plants and microorganisms and 2) Development of promising compounds into drugs.

The project

Within the Objective 1 we will create a collection of 1000+ unique Actinobacteria strains, a corresponding number of culture broth crude extracts, and 100+ plant crude extracts. Metabolites in the crude extracts will be separated into 5000+ fractions and these will be tested for a broad spectrum of biological activities, particularly against clinically important pathogenic microorganisms (including MDR strains). These include Mycobacterium tuberculosis (causing tuberculosis), G- bacteria, Plasmodium falciparum (causing malaria), Zika virus, and others.

The Objective 2 aims to the development of previously patented hybrid lincosamide derivatives developed by the Czech team and further compounds suggested by SEA teams into drugs.

The science

Our strategy to combat the antibiotic (antibacterial and antiparasitic) crisis exploits natural products that proved to be a superior source of druggable compounds. We will use modern biology and chemistry methodology for this purpose – knowledge-based genome mining (oriented on the search for biosynthetic pathways utilizing alkyl-proline derivatives, which are far more efficient when compared to L-proline incorporating compounds), mass spectrometry-based metabolomics (GNPS molecular networking + other bioinformatics tools); and we will focus on testing multiple targets, i.e. multiple pathogens including those clinically most important and threatening. CZ team will provide a collection of the clinically most dangerous bacterial strains from the WHO list for antimicrobial activity testing; Thai team possess a collection of P. falciparum strains for antimalarial properties and resistant M. tuberculosis strains for antimicrobial properties testing. Unique sources of bioactive metabolites from yet underexplored Thai and Indonesian biotopes will be used to search for new compounds.

Project partners:

Institute of Microbiology, Czech Academy of Sciences, Czech Republic (PI and main coordinator - Jiri Janata)

School of Pharmacy, Walailak University, Thailand  (PI and coordinator for SEA - Amit Jaisi)

Faculty of Pharmacy, Andalas University, West Sumatra, Indonesia (Deri Dachriyanus)

Research Centre for Chemistry, Indonesian Institute of Science (LIPI), Indonesia (Abdi Wira Septama)

Contact:

Jiri Janata, Ph.D.                   

Background

Lithium-ion batteries with high energy density are crucial to meet the ever-expanding demands of portable electronic, electric vehicles, and large-scale energy storage. Traditional and most commercialized lithium-ion batteries use graphite and lithium metal oxides as the materials for the intercalation-based anodes. Despite their good cycling stability, such materials possess low capacity limiting the high energy density applications of the lithium-ion batteries (e.g., stationary energy storage and electric vehicles). Various anode materials have been investigated as an alternative to overcome that issue, including silicon, which is the second most abundant element in the earth’s crust. Silicon has ultra-high theoretical capacity of 4200 mAh g-1, which is about ten times higher than that of graphite anodes. However, drastic volume expansion of silicon materials during the battery operation leads to mechanical failures, loss of electrical contact, and undesirable side reactions, leading to the poor cycle life of the batteries and hinder their large-scale commercialization. Meanwhile, rapid development in the field of nanotechnology has uncovered many exciting properties of nanomaterials, including silicon nanostructures for energy storage applications. Many advances in the energy storage technology could not have been possible without enormous efforts and improvements in nanotechnology, in which understanding and manipulating the physicochemical of the materials with the desired properties at the nanometer scale had become the keys for innovation. 

The Project

The objective of the SiNanoBatt project is to use low-cost semiconductor nanomaterials (i.e., 3D silicon nanostructures for anodes) and top-down nanotechnologies to realize lithium-ion rechargeable batteries with high energy density and long cycle life. The silicon-based materials will be nano-engineered to alleviate the effect of volume expansion of silicon. Hence, we can prevent the capacity losses, improve the cycle life, and enhance the C-rate performance of the batteries. Two main strategies will be introduced for the anode design: (1) to use the 3D silicon nanostructures with different architectures and crystal orientations and (2) to integrate them with carbon or polymeric frameworks for creating novel hybrid carbon/polymeric/silicon nano-anodes. Such approaches are expected to be able to accommodate the volume expansion on the silicon anode without losing the structural integrity and mechanical stability during the lithiation process. Furthermore, the experimental works will be supported by theoretical studies (i.e., modeling of silicon nanomaterials and packing capacity of lithium-ion in the anodes) to understand the effects of the proposed approaches at the atomic scale.

The Science

SiNanoBatt enables a top-down fabrication of well-controlled and vertically-aligned 3D silicon nanostructures that are employed as an anode for lithium-ion batteries. Different 3D vertical silicon architectures will be realized (e.g., vertical silicon nanowires with various geometries), in which they are expected to be able to maintain high electrical conductivity, obtain good ionic conductivity, and exhibit robust structural integrity during the lithiation/delithiation processes. Various nanopatterning techniques (e.g., photolithography, nanoimprint lithography, and colloidal nanosphere lithography) will be utilized to fabricate the desired structures. Moreover, those well-tailored silicon nanoplatforms will be integrated with carbon-based materials and polymeric networks to enhance the battery performance by creating such unique hybrid nanostructures with higher conductivity and stronger mechanical properties.

The Team

The SiNanoBatt partners are:

• Dr.-Ing. Hutomo Suryo Wasisto, Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Technische Universität Braunschweig, Germany (Project Coordinator)
• apl. Prof. Dr. Erwin Peiner, Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Technische Universität Braunschweig, Germany (Project Coordinator)
• Dr. Afriyanti Sumboja, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Indonesia
• Prof. Dr. Vudhichai Parasuk, Department of Chemistry, Faculty of Science, Chulalongkorn University, Thailand
• Nursidik Yulianto, M.Eng., Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Technische Universität Braunschweig, Germany
• Andam Deatama Refino, M.Sc., Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Technische Universität Braunschweig, Germany

Contact:

Dr.-Ing. Hutomo Suryo Wasisto, e-mail: h.wasisto@nanosense-id.com

apl. Prof. Dr. Erwin Peiner, e-mail: e.peiner@tu-braunschweig.de

Background

Resistance to antibiotics is considered to be one of the major health problems worldwide. Unfortunately, the rate of development of new drugs is too slow to address the need that is apparent by alarming reports on multiply resistant bacteria against which no antibiotics work. Among the pathogenic bacteria Staphylococcus aureus (SA) is one of the most common human pathogens that can be either hospital acquired or community associated. SA is particularly prone to acquire resistances to most antibiotics. Although infection rates differ considerably among various countries, MRSA (Methicillin-resistant Staphylococcus aureus) is a worldwide concern in health care facilities, i.e. also in Asia, and represents a severe infection disease burden, in particular in the ageing population. The necessary screening methods are typically expensive and require laboratory facilities. To be able to screen patients in hospital admission, to administer antibiotics in a targeted fashion (i.e. to match the drug to the bacterium) and to analyze pathways of resistance spread, reliable on-site tests are absolutely necessary. These should be rapid, ultrasensitive, selective and accurate, yet also economic and sustainable.

The project

NAPARBA aims at the development of a reliable and sustainable nanotechnology-enabled approach to ultrasensitively detect and differentiate antibiotic-resistant bacteria in a point of care diagnostic setting. The project addresses the core challenge to detect bacteria and in particular to differentiate resistant from non-resistant strains at low concentrations of potential biomarkers. The approach developed in NAPARBA to separate, up-concentrate and analyze small amounts of DNA will tested for applicability in a prototypical demonstrator to ensure applicability in a working environment.

The science

NAPARBA builds on a versatile and ultrasensitive detection approach, enhances the functionality and performance of the individual components and also utilizes nanoparticles of local natural resources. These are complemented by to be improved high performance non-toxic luminescent quantum dots for signaling, magnetic nanoparticles for separation and nanocoatings of advanced polymers to suppress particle aggregation and to afford functionality. The nanotechnology elements are combined in a point of care (POC) compatible workflow employing low cost materials and are tailored towards prototypic application.

The team

The NAPARBA partners are:

Prof. Dr. Holger Schönherr, Physical Chemistry I and Research Center of Micro and Nanochemistry and Engineering (Cμ), University of Siegen, Germany (Project coordinator)

S. N. Aisyiyah Jenie, Ph.D, Research Center for Chemistry, Indonesian Institute of Sciences, Indonesia

Associate Prof. Dr. Sedat Nizamoğlu, Koç University, Turkey

Contact:

Prof. Dr. Holger Schönherr           E-Mail: schoenherr@chemie.uni-siegen.de

The Background

Climate change and socio-economic growth are projected to severely challenge river basin development worldwide, calling for robust planning solutions with respect to such uncertain and evolving conditions. This is particularly relevant in monsoonal Southeast Asia, where large water storage systems play a key role for securing water, energy, and food to a rapidly growing and changing society. These systems require robust and adaptive operations capable of coping with high intra-annual and inter-annual hydroclimatic variability and to increasing frequency of extreme events. They also have to face multi-sector changing demands across multiple time scales, from daily operation to strategic river basin development.

The Project

The ambition of the project is to develop a decision analytic framework for supporting the robust, strategic planning of river basins in monsoonal areas with respect to future changes in water availability (climate change) and demands (socio-​economic and technological changes). The framework will integrate future climate scenarios, including a catalogue of extreme climate events, future water demand scenarios, and a high-​resolution infrastructure-​accounting hydrological model to build accurate projections of water availability that also include water management policies optimized by means of a strategic model, against which to assess sustainability and robustness of future river basin development plans. The focus will be on the Red River Basin, China-​Vietnam, a large transboundary river basin, where conflicts among different water uses, including hydropower production, flood control and water supply, and negative impacts on long-​term sustainability are expected to increase under the combined pressure of increasing water and energy demands, and climate change. Particularly, extreme weather events are expected to become more frequent and extreme.

The Science

REBECCA will advance the current state-of-the-art from different scientific disciplines and integrate it within a multi-dimensional and multi-disciplinary framework to support the robust, strategic planning of water infrastructures in river basins that will be highly impacted by climate and socio-economic changes, with a focus on monsoonal areas. The project will bring the current state-of-the-art of integrated water resources management a step further by: (i) developing a decision analytic framework that explicitly integrates multiple models and their feedbacks, including a detailed characterization of the co-variance between future hydro-climatic and socio-economic changes; (ii) quantifying the impacts of future hydro-climatic and socio-economic scenarios on water resources, planned infrastructures and strategic development plans of decision makers; (iii) identifying robust planning options (e.g., multi-purpose water reservoirs) that are able to deal with a vast array of highly uncertain future changes and still perform satisfactorily with respect to economic, environmental and societal aspects in order to foster environmentally and economically sustainable growth.

The Team

Project coordinator: Prof. Dr. Paolo Burlando, Institute of Environmental Engineering, ETH Zurich, Switzerland

Prof. Dr. Andrea Castelletti, Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Italy

Dr. Anna Costa, Institute of Environmental Engineering, ETH Zurich, Switzerland

Prof. Dr. Andreas H. Fink, Institute of Meteorology and Climate Research, Karlsruhe Institute of Technology, Germany

Dr. Roderick van der Linden, Institute of Meteorology and Climate Research, Karlsruhe Institute of Technology, Germany

Dr. Van Anh Truong, Meteorology and Hydrology Faculty, Hanoi University of Natural Resources and Environment, Vietnam

Contact: Prof. Dr. Paolo Burlando, Dr. Anna Costa